Ask X3What does 49 CFR 40.90 (What criteria do laboratories use to establish that a urine specimen is invalid?) require?
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Based on 49 CFR 40.90, laboratories must follow these specific requirements to establish and report an invalid urine specimen:
* Use Proper Criteria: Apply the invalid test result criteria required by the HHS Mandatory Guidelines for both initial and confirmation testing (49 CFR 40.90).
* Use Separate Aliquots: Test two separate aliquots from the specimen—one for the initial test and another for the confirmation test.
* Consult with the MRO: If a specimen is invalid for a reason outlined in the HHS Mandatory Guidelines, the laboratory must contact the Medical Review Officer (MRO) to discuss whether sending the specimen to another HHS-certified laboratory would help achieve a positive or adulterated result.
* Report Specific Details: Report invalid results according to the HHS Guidelines, including the specific reason the test is invalid and the supporting numerical values (such as pH) where appropriate.